Majid Hajifaraji; Fatemeh Jahanjou; Fatemeh Abbasalizadeh; Naser Aghamohammadzadeh; Mehran Mesgari Abbasi; Neda Dolatkhah
Volume 19, Issue 6 , June 2017, , Pages 1-10
Abstract
Background: Despite progress in the control and treatment of gestational diabetes mellitus (GDM) in pregnant females, these patients remain at risk of disease complications.Objectives: The present study aimed at investigating the effect of probiotic supplements on Systolic Blood Pressure (SBP) and Diastolic ...
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Background: Despite progress in the control and treatment of gestational diabetes mellitus (GDM) in pregnant females, these patients remain at risk of disease complications.Objectives: The present study aimed at investigating the effect of probiotic supplements on Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) in pregnant females diagnosed with GDM.Methods: This randomized double-blind, placebo-controlled trial randomly assigned 64 pregnant females with GDM, recruited through convenience sampling, to either a group receiving a probiotic capsule (n = 32) or a group receiving a placebo (n = 32) for 8 weeks in Tabriz, Iran, during the spring and summer months of 2014. Their blood pressure was measured at baseline and at 2-week intervals, up to 8 weeks.Results: A total of 56 subjects completed the study. There was no significant difference in SBP in the probiotic group at any time compared with that at onset, yet, SBP increased significantly in the placebo group. The declining trend of DBP was evident in the probiotic group at 2 weeks and continued to the end of the study; however, DBP had increased slightly by week 6 in the placebo group. There were significant differences between the probiotic and placebo groups at 6 and 8 weeks, respectively, for SBP (104.828 (2.051) mmHg vs. 112.963 (2.126) mmHg; P = 0.008) and (106.552 (1.845) mmHg vs. 115.185 (1.912) mmHg; P = 0.002) and for DBP (62.414 (1.353) mmHg vs. 70.741 (1.402) mmHg; P < 0.001) and (60.690 (1.540) mmHg vs. 71.296 (1.596) mmHg; P < 0.0010).Conclusions: The results demonstrated that consumption of probiotic supplements for 8 weeks prevented an increase in SBP and decreased DBP in pregnant females diagnosed with GDM.
Samieh Ghana; Sevil Hakimi; Mojgan Mirghafourvand; Fatemeh Abbasalizadeh; Nasser Behnampour
Volume 19, Issue 4 , April 2017, , Pages 1-8
Abstract
Background: Wound complications and pain are major causes of morbidity after cesarean section (CS). Although medications are safe for use by mothers after CS, many females prefer non-pharmaceutical methods. An abdominal binder is a complementary therapy, commonly used post-major abdominal surgery.Objectives: ...
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Background: Wound complications and pain are major causes of morbidity after cesarean section (CS). Although medications are safe for use by mothers after CS, many females prefer non-pharmaceutical methods. An abdominal binder is a complementary therapy, commonly used post-major abdominal surgery.Objectives: There is limited evidence about the effect of abdominal binders. The aim of this study was to investigate the effects of an abdominal binder on wound healing and consumed pain medication.Methods: This randomized controlled trial included 178 females, who had undergone non-emergency CS at 1 of the 3 hospitals in Gonbad-e Kavus, and Golestan, northeast of Iran. In the intervention group, patients were administered abdominal binders, in addition to routine care. The binder was used for 2 days after the patient was admitted to the surgery ward. The control group received routine care. We used the demographic data questionnaire, questionnaire for cataloguing analgesic medications taken by participants (each 6 hours after CS), and Redness, Edema, Ecchymosis, Discharge, Approximation of wound edges (REEDA) scale for assessment of wound healing. The participants provided their written consent for participation in this study.Results: The mean (SD) age of the participants was 26.3 (5) years. Mean (SD) REEDA score was 0.4 (0.5) in the intervention group and 0.5 (0.8) in the control group. The median (quartile 25-75) REEDA score was 0 (0-1) in both groups. Mean REEDA scores did not differ significantly between the 2 groups (P = 0.724). Significant differences were observed in the approximation of wound edges in the intervention group 5 days post-CS (P = 0.007). Administered analgesic medications did not differ significantly between the 2 groups (at 6 hours in suppository, and 6 and 24 hours post-intervention in intramuscular of injection narcotics). Significantly fewer analgesic medications were administered in the intervention group when compared with the control group (P = 0.001). Satisfaction did not differ significantly between the 2 groups (P= 0.443).Conclusions: In this study, the abdominal binder was effective in pain medication consumption at some intervals. However, it had no healing effect on CS scars.
